The human papilloma virus

The human papilloma virus

Many infections do not cause symptoms in healthy people.The immune system stops the activities of the virus, as a result of a person's carrying of an infection.At the same time, the transmission of other people of pathogenes, with a complete clinical well, because the viral particles are in full clinical and compliance because of the patient's biological liquids.The secret infection course may be the main reason for a significant spread of the disease: patients are not subject to timely examinations, and other people continue to be unconsciously.

Human Papilloma virus (HPV) can be called an excellent example of a secretive agent.Most people have been infected with at least one type of HPV in lifetime, but the clinical manifestations of the disease do not occur in all cases.The doctors increase the risk of a malignant tumor to aggravate the increasing risk of the risk.Moreover, patients suffering from immunization often lead to such a negative result of the disease.Topic medications help to invest the symptoms of HPV infection.It is also recommended in the timely vaccine.

More about the disease

The human papilloma virus is the pathogenic of an infection affecting the skin and mucous membranes of the bodies.The main manifestation of the disease is the growth of neoplasms in the region, the gender of the oral cavity and the throat.In some cases, papillomas, processed places, processed places such as the skin of the lower and upper limbs.Localization of warts depends on the type of HPV.Most people caused the secret transportation of infection infection, but it begins to show the virus virus by decreasing immunity.In some cases, immunocompetent cells are independently destroyed within 3-6 months after the occupation of the pathogenic body.

HPV infection is the most commonly transmitted disease.In most such indicators, the virus and asymptomatic pathological flow can be explained by high virullah.The use of condoms does not always prevent infection, so the patient can even continue to spread protected sexually protected sex.At the same time, experts have developed effective vaccines that prevent the development of the oncogenic form of HPV.Immunization should be instilled in the first sex for adolescents, to protect the virus.

Features of the virus

Human Papilloma virus is pathogenous in containing an DNA.Unlike bacteria and other microorganisms, the viruses can only show their activities after submitting their activities to the cage and place their genetic information in the nucleus.After that, the affected cell began to synthesize the proteins necessary for the parliament of viral particles.Papillomavirus almost all representatives of the family attacked only one type of organism, and HPV infection can only happen in people.

Scientists know more than 600 sushes (type) of the Papilloma virus, which are different with genetic information.40 types of HPV types cause mucous membranes and forms of different damage to the skin.At the same time, the classification of the tensogenic degree of the strains is important in clinical significance.Thus, women's cervical cancer happens with the occupation of the most HPV 16 and 18.These infectious agents are not always indicated by skin changes.

Surprisingly on the basal floor of HPV epithelial.The pathogen may be available in the form of an episome not associated with cell DNA or is available in the form of an integrated form associated with the cell genome.The integrated virus produces the necessary proteins and leads to clinical manifestations of the disease.The life of HPV in the body is not a direct cause of malignant tissue degeneration, but the transportation of the virus increases the threat of risk factors for cancer.

Infection methods

The virus is in basic epitelic cells, so any microcracy of skin and mucous machines increases the risk of infection.In most cases, HPV is transmitted vaginal, anal or oral contact.The condom can only be provided with part of the skin surface, but viral particles can still penetrate the body through other covers.The presence of genital furnaces tends to transmit pathogen, but it is a source of HPV in the externally intact skin of the disease.

Other transfer ways

  1. Child's infection during childbirth.Children have the most respiratory defeats
  2. Independent transfer from one part of the virus to another
  3. General use of personal hygiene items, including razor, toothbrushes and towels
  4. Blood transfer.Recent studies have confirmed the probability of transfusion infection.
  5. Surgical interventions in stipping conditions

Despite the various reasons for viral occupation, it is only a sexual way of the HPV infection.Other sources of infection are characterized by low risk of pathogen.

Risk factors

In addition to the direct paths of the transfer of HPV, it is necessary to take into account the role of risk factors.We are talking about human lifestyle and features of certain physical situations.

Basic risk factors for infection

  1. A large number of sexual partners.Safe sex, a quick and subsequent activity leads to infection.
  2. Age.In most cases, genital warts are found in teenagers and young patients, oral space and air conditioning of the respiratory system are characteristic of children.
  3. Weakened immunity system.Patients suffering from HIV infection or immunization obtained are high in the risk of viral occupation.In addition, HPV is more symptomatic than the transplantation of the organs.
  4. Damage to skin and mucous membranes.Microtraumas facilitates the virus to enter the basal layer of the epithel.
  5. Smoker and alcoholism.Bad habits weaken immunity.
  6. Venate infections.

In addition, pregnant women include the risk of infection.It should be noted that the elimination of incentive factors in the disease is effective preventive tactics.

Clinical picture of papilloma

Clinical current

The incubation period that prevents symptomatic manifestations of the disease may last a few months or not.In the immunocpetent patients, the body can destroy the infection during this period, but the spontaneous removal of the pathogen does not always happen.A person may be infected with several sushes of the virus at the same time.Signs of HPV infection occur when exposed to negative factors that weaken the immunity of tissues.Due to the repetitive course, the condiloma disappears periodically and is re-formed.Oncological complications of the infection can develop in several decades.

Possible results of the disease:

  1. Cervical carcinoma - malignant neoplasm of epithelial tissue.This type of oncology is only associated with the human papilloma virus.With timely vaccine, the risk of oncogenesis is reduced.
  2. The carkinoma of the plant-anal hole.This type of complication can occur in men and women.Early symptoms of anus cancer include bleeding and skin itching.
  3. Urogen violation due to urethra barrier by condioma.
  4. The malpractice of warts in the throat and mouthpiece.

Cervical cancer is one of the most common reasons for women's death.Since this disease is related to viral invasion, a gynecologist needs regular examinations.Modern vaccinations protect women from the most oncogenic species.

Diagnosis

Gynecologists, urologists, veningologists and dermatologists are examined by condyl.During the preliminary destination, the doctor will ask the patient's complaints, collecting the Anamnestic information and hold skin formation.Typically, HPV manifestations are easily identified, but other diseases should be ruled out.To do this, the specialist will determine instrumental and laboratory research.

Required Diagnostic Methods:

  1. Instrumental examination of vagina and cervix (colposcopy).Such a research is definitely carried out with a cervical carcinoma.During the examination, the doctor may discover more than one papillom and epithelial dysplasy areas.
  2. Biopsy - to get tissue outfit in the field of skin or mucous changes.A sitological study of the sample allows you to identify malignant cells.
  3. Polymeraz chain reaction - detection of HPV viral particles in the body.The conduct of this test allows the doctor to set pathogenic tension and viral burden.
  4. Digene test is the high accuracy of the DNA of the oncogen strains of the Papilloma virus.The research is used as a valid choice.
In addition to these studies, the doctor will recommend taking tests for other infectious diseases, including HIV and syphilis.

Drug treatment

Preparations for HPV infection can only eliminate the symptoms of the disease and prevent the generation of tissue.It is impossible to completely remove the virus using drug therapy.Oral and topical agents are determined when there is high risk of oncogenesis, immune deficiency and other negative conditions.If the virus does not indicate itself with foreign changes, generally general preventive measures.

Possible meetings

  1. Salicylic acid to remove the wirs.Not used to process the skin of the face and genitals.
  2. Creams and ointments with immunomoduly.
  3. Podofilo - an ointment with a sitostatic effect.Application to the affected skin causes the destruction of pathogenic elements.
  4. Trichlooroccic acid for the chemical cause of general and sexual warts.Can cause a local part.

The listed medications should be used only under medical control.After the removal of Warts, the HPV infection can re-reflect itself and can even spread to other areas.

Surgery

Surgical treatment of papilloma

The doctor can offer the patient's surgical and minimally invasive methods to delete the warts.Typically, such methods do not cause aggravations, but after the intervention, the bleeding of tissues can occur in the first days.

Types of intervention:

  1. ordinary surgical conviction;
  2. Frozen with liquid nitrogen by destroying the affected tissues;
  3. Electric clotting;
  4. Removal of papiles with lasers;
  5. Using a "knife" from a radio wave.

All procedures are conducted under local anesthesia.The specialist will select the safest method for the treatment of air conditioning.

Predict

The course of papillomavirus infection depends on the patient's immune status and a certain virus tension.About 30% of the population has a spontaneous removal of pathogenes caused by active immunity.Symptomatically, the disease often shows itself in patients with pregnant women, children, old people and immunodefey.

HPV infection is characterized by a repetitive course.The shape papillomas can gradually disappear or spread to the neighboring skin.Oncogenic strains of the virus affect the most cervical mucous membrane and eventually increase the impact of malignant tissue degeneration, such as epithelial dysplasy, smoking and use mouth contraceptives.The tumor can occur 10-20 years after the occupation of the virus.

Prevention

The most reliable method of prevention early immunization.Gardasil vaccine with viral proteins and auxiliary components is effective against HPV 6, 11, 16 and 18 types.If the vaccine was held early until the first sex is the first sex, the risk of subsequent development of cervical cancer is not more than 1%.

Additional prevention:

  1. the use of condoms;
  2. Only sex with reliable partners;
  3. Comprehensive personal hygiene;
  4. Gynecological examination at least once a year.